{
    "collection": [
        {
            "collection": [
                224820,
                25287
            ],
            "type": "INCLUDE"
        },
        {
            "collection": [
                19884,
                29870
            ],
            "type": "EXCLUDE"
        }
    ]
}

In the above example, the collections property of the outer Audience Targeting Object contains 2 Audience Targeting Restrictions Objects.

Each Audience Targeting Restrictions Object contains a set of custom audiences to include or exclude.

📘
If you created any custom audiences with exclude_from_campaigns = true, then those custom audiences will be excluded from all campaigns.
Campaigns that you create going forward will have this exclusion by default. Moreover, the exclusion will be applied to your previously existing campaigns.